Hi, Randie, I agree with Tressie's comment about the possible need for pain management. In addition, if part of the problem really is that prednisone is ineffective your vet could try a different corticoid steroid. I had a ferret with a very different medical situation who simply did not respond to pred. Dexamethasone was used instead which worked well for him. You might want to discuss that possibility with your vet. The usual disclaimer applies: I am not a vet. I don't even play one on TV. Thinking good thought for you and to Lillie. All the best, Caity with Zephyr and Chin Soon [Posted in FML 7199]