I've had ferrets for about 14 years and have always had cats in the house as well. All of my cats have gotten along with the ferrets but only some play with them. I think cats tend to view ferrets as kittens since they're so active and playful. And since they're equal on the food chain I've never seen any prey/hunter interaction, well, unless it's the cat hunting the ferret LOL I think the most important thing is to make sure the cats have an "out" - a chair they can jump to to get away from the ferrets, a baby gate they can go past to be completely ferret free if they want. I also keep all my cats' claws trimmed VERY close. I have put my hand in while a cat's slapping to see if the claws are out, though, and they never have been But better to be safe. I also never leave my ferrets out unsupervised. Percy, a Persian I adopted five years ago when he was two, fell in love with them instantly - even sleeping on top of their cage until I'd let them out. He loves to grab them and groom them like mad and has always played and groomed the females far more often than the males. Currently he's absolutely in love with Mitzy, a little one year old I adopted last year. He also plays with Bitzy, who's slightly younger. Bitzy does something I've never seen a ferret do and it drives Percy completely mad. She'll play dead - lay there completely still while he meows at her and even paws at her. His meows get increasingly louder and more annoyed till he finally gets bored and walks away. She then jumps up, gives him a hiss and dashes off LOL Will have to get this on video because it's just too cute. And you can tell it really bothers Percy that she's "dead". I have oodles of ferret/cat interaction on my Youtube page. Here's one of Percy with the whole gang several years ago: http://www.youtube.com/watch?v=WFG8eGHDUu8 Percy with Roxy - who he completely adored. He really mourned her loss and I really HAD to get a new female once she passed. http://www.youtube.com/watch?v=DITq0PVpvN4 Penny, my adopted Exotic Shorthair playing with the ferrets http://www.youtube.com/watch?v=PvbRq_Xu97c Recent vids with Percy and the new girls Bitzy and Mitzy: http://www.youtube.com/watch?v=AqPAKpcmTa0 http://www.youtube.com/watch?v=dRKR6KI0sgM Laura [Posted in FML 7151]