http://www.ncbi.nlm.nih.gov/pubmed/21696122 >J Vet Dent. 2011 Spring;28(1):8-15. >Oral examination results in rescued ferrets: clinical findings. > >Eroshin VV, Reiter AM, Rosenthal K, Fordham M, Latney L, Brown S, >Lewis JR. > >Source >Matthew J. Ryan Veterinary Hospital of the University of Pennsylvania, >Philadelphia, PA 19104-6010, USA. > >Abstract >Ferrets have increased in popularity as pets, and a growing number are >seen in companion animal practice. Domestic ferrets are commonly used >as animal models for research of human oral conditions. The present >study evaluated the prevalence of oral pathology in rescued ferrets >which - to the authors' knowledge - has not yet been described in the >scientific literature. Conscious oral examination was performed on >63 ferrets, of which 49 underwent general anesthesia for further >examination. The most common clinical findings included malocclusion >of mandibular second incisor teeth (95.2%); extrusion of canine teeth >(93.7%); and abrasion and attrition of teeth (76.2%). Tooth fractures >were exclusively associated with canine teeth and found in 31.7% of >ferrets. Pulp exposure was confirmed in 60.0% of fractured teeth. >[Sukie Note: that is in about 19% of the total number of ferrets when >you multiple 31.7% by 60%] The normal gingival sulcus depth measured > <0.5-mm in 87.8% of anesthetized ferrets. Clinical evidence of >periodontal disease was present in 65.3% of anesthetized ferrets >(gingivitis or probing depths > 0.5-mm), however advanced periodontal >disease (i.e. periodontal pockets > 2-mm or stage 3 furcation >exposure) was not found upon clinical examination. There was no >evidence of tooth resorption, dental caries, stomatitis, or oral >tumors in the examined group of ferrets. > >PMID: 21696122 [PubMed - in process] for those in Australasia: >Vaccine. 2011 Jun 18. [Epub ahead of print] >A recombinant Hendra virus G glycoprotein-based subunit vaccine >protects ferrets from lethal Hendra virus challenge. >Pallister J, Middleton D, Wang LF, Klein R, Haining J, Robinson R, >Yamada M, White J,Payne J, Feng YR, Chan YP, Broder CC. > >Source >CSIRO Livestock Industries, Australian Animal Health Laboratory, >5 Portarlington Road, Geelong, VIC, 3220, Australia. > >Abstract >The henipaviruses, Hendra virus (HeV) and Nipah virus (NiV), are two >deadly zoonotic viruses for which no vaccines or therapeutics have yet >been approved for human or livestock use. In 14 outbreaks since 1994 >HeV has been responsible for multiple fatalities in horses and humans, >with all known human infections resulting from close contact with >infected horses. A vaccine that prevents virus shedding in infected >horses could interrupt the chain of transmission to humans and >therefore prevent HeV disease in both. Here we characterise HeV >infection in a ferret model and show that it closely mirrors the >disease seen in humans and horses with induction of systemic >vasculitis, including involvement of the pulmonary and central nervous >systems. This model of HeV infection in the ferret was used to assess >the immunogenicity and protective efficacy of a subunit vaccine based >on a recombinant soluble version of the HeV attachment glycoprotein G >(HeVsG), adjuvanted with CpG. We report that ferrets vaccinated with a >100ug, 20ug or 4ug dose of HeVsG remained free of clinical signs >of HeV infection following a challenge with 5000 TCID(50) of HeV. In >addition, and of considerable importance, no evidence of virus or >viral genome was detected in any tissues or body fluids in any ferret >in the 100 and 20ug groups, while genome was detected in the nasal >washes only of one animal in the 4ug group. Together, our findings >indicate that 100ug or 20ug doses of HeVsG vaccine can completely >prevent a productive HeV infection in the ferret, suggesting that >vaccination to prevent the infection and shedding of HeV is possible. > >Copyright (c) 2011. Published by Elsevier Ltd. > >PMID: 21689706 [PubMed - as supplied by publisher] Sukie (not a vet) Recommended ferret health links: http://pets.groups.yahoo.com/group/ferrethealth/ http://ferrethealth.org/archive/ http://www.afip.org/ferrets/index.html http://www.miamiferret.org/ http://www.ferrethealth.msu.edu/ http://www.ferretcongress.org/ http://www.trifl.org/index.shtml http://homepage.mac.com/sukie/sukiesferretlinks.html all ferret topics: http://listserv.ferretmailinglist.org/archives/ferret-search.html "All hail the procrastinators for they shall rule the world tomorrow." (2010, Steve Crandall) On change for its own sake: "You can go really fast if you just jump off the cliff." (2010, Steve Crandall) [Posted in FML 7104]