The Deslorelin implant with (4.7mg implant) research was started in Holland about 5 years ago by Dr Nico Schumaker, It was, at that time intended to be used as a substitute to neutering in the hope that ferrets would not get Adrenalin tumors. My ferrets are now 5 years old, have full beautiful coats, they get along fine, do not smell and do not fight, and have not been neutered, they got their first implant at 3 months old. I think the secret is to have the implants done before they get tumors, As I understand it from Nico, if a ferret all ready has adrenalin that has developed for to long, the implant will not help, it might still be necessary to have one adrenal gland removed and then try the implant to slow the process in the second adrenalin gland. Hope this helps Cheers Stephenie Netherland [Posted in FML 6780]