Just a little more: If enough tissue remains the ferret will produce those steroids on his/her own. If enough does not remain now then the ferret will either need the meds temporarily or permanently depending on which tissues regrow at which rate over time. Yes, it is possible to regrow the hormonal tissue of the tumor faster than the normal steroid producing normal tissues if not all of the affect tissue could be removed so a ferret can have adrenal disease (in which case Lupron Depot or Suprelorin will be used) while still needing meds to avoid going Addisonian. In some ferrets after adrenal surgery regular use of slowly releasing Lupron Depot (not the 24 hour form of Lupron which can even worsen adrenal disease) or Suprelorin (not the horse form of deslorelin which is not time release so carries the same risk as the 24 hour Lupron) is done routinely on a regular schedule after a diseased adrenal has been removed to try to avoid or treat potential problems with the other one. Sukie (not a vet) Recommended ferret health links: http://pets.groups.yahoo.com/group/ferrethealth/ http://ferrethealth.org/archive/ http://www.afip.org/ferrets/index.html http://www.miamiferret.org/ http://www.ferrethealth.msu.edu/ http://www.ferretcongress.org/ http://www.trifl.org/index.shtml http://homepage.mac.com/sukie/sukiesferretlinks.html all ferret topics: http://listserv.ferretmailinglist.org/archives/ferret-search.html "All hail the procrastinators for they shall rule the world tomorrow." (2010, Steve Crandall) [Posted in FML 6756]