This is a very important topic that needs as many responses as possible. Almost 100% of ferret owners will face this issue. When is it time to separate a group of ferrets? When one ferret in the group goes adrenal and misbehaves? You never want a ferret to "have to" live alone, but when is that the only option? My individual problem follows, but feel free to address the other questions above. I have an established group of ferrets that, when not out playing, live in a very large cage together. My big guy is adrenal, but he never shows it inside the cage. But, when I let him out to play, he plays very rough with his cagemates, no matter the adrenal med. The two he bothers the most squeak and squeal, but the big one never leaves a mark -- no puncture or scratch. He isn't sucking the hair off their ears, which would be a normal adrenal behavior. The big one will chase and chase them for ten minutes without stopping. Is this a case of the big one can live with them, but he can't play with them, or, because he isn't leaving any physical damage, he can stay and play and I'm just being an over-protective mom? [FV] [Posted in FML 6657]