Yes, that can happen, though often the people are allergic to something ON the ferret like a deodorizing spray, litter fragments, treat oil, etc. When people become inflamed after a scratch that typically is just because of waste and litter caught in claws which entered the wound. That there are people who are truly allergic to ferrets is well known and documented, though it is rare compared to dig, cat, or bird allergies. The most serious allergies (such as anaphylactic reactions) typically are in people who also are allergic to cats who have been exposed to whole male ferrets (or sometimes to ferrets with adrenal disease). Some then can have it generalize to other ferrets. Of course, there simply are people who are allergic to any ferrets, too, especially after many exposures. If you search you will find a medical paper on a man who survived a particularly nasty anaphylactic reaction to a ferret. It predates much of the PubMed content, though, so may not be there. We have not had need of it so I don't personally have records of it but in past issues of the Ferret Mailing List someone has told of a laboratory which can custom make serum for allergy shots or allergy SLIT treatment (Sublingual Immunotherapy). The URL of the FML Archives is in the header of each day's FML and also in my sig lines. Sukie (not a vet) Recommended ferret health links: http://pets.groups.yahoo.com/group/ferrethealth/ http://ferrethealth.org/archive/ http://www.afip.org/ferrets/index.html http://www.miamiferret.org/ http://www.ferrethealth.msu.edu/ http://www.ferretcongress.org/ http://www.trifl.org/index.shtml http://homepage.mac.com/sukie/sukiesferretlinks.html all ferret topics: http://listserv.ferretmailinglist.org/archives/ferret-search.html "All hail the procrastinators for they shall rule the world tomorrow." (2010, Steve Crandall) [Posted in FML 6570]