Although I have no experience wwith squamous cell carcinoma in ferrets, I had done some casual research on it since one of my ferrets had some gingival overgrowth that I feared might be SCC. I found nothing about cryosurgery, etc. The standard procedure for SCC involves wide-margin excision, often including removal of part of the jaw/bone. SCC tumors are agressive and commonly spread before a lesion is even noticed. Radiation and/or chemo seem to be ineffective on oral SCC. From what I've read surgery may extend the ferret's life by about 6 months. I will say that ferrets do not need vitamin D - in fact, it's easy to give them too much. I recommend going to a holistic ferret vet for supportive therapies since we may do more harm than good if we treat self-treat our ferrets without proper guidance. There are some herbal type treatments that have proven effective against cancers in some ferrets. A number of these remedies are based upon the Hoxsey formula, which was studied and deemed potentially effective at the Mayo clinic. If you opt in favor of traditional treatments, I recommend consulting with a holistic/integrative vet for supportive supplements anayway. If you choose to work with two different vets, the vets must know the details of each treatment. Depending upon the treatments, both vets may need to collaborate in order to provide a sound treatment plan For example, somple nutritional supplements such as fish oil and nutritional greens would not require collaboration. But your primary care vet will need to know what/how much, etc. is being added to the diet. In contrast, an herbal cancer treatment would need to be carefully managed if it were to be coupled with surgery. For this type of approach (which may NOT be feasible) the two vets must be working together. I tend to rely on traditional medicine. However, I have used alternative approahes, sometimes coupled with traditional therapies. I've been amazed at the success rate I've seen with the alternative treatments. Since I tend to be a skeptic, I place greater confidence in "tried aand true" medicines that are of known/controlled potencies. But I have to admit that I have witnessed some amazing healing (even with lymphoma) using nutritional support guided by a good holistic vet. -jennifer [Posted in FML 6537]