The 5 vets I've spoken to and have seen for one of my ferrets have all told me that flutamide works the best. I'm not sure but if I remember correctly, one of them said it's because Flutamide controls the right hormones that Propecia doesn't. However, in my limited experience with Propecia and Flutamide, Flutamide just made my ferret look "green" in that he looked like he wasn't feeling well and kept flattening himself and just looked like he was going to be sick. I am giving him Propecia along with ferretonin and Lupron depot but I can't help but to think how much better he may be doing if I were to put him back on Flutamide. If you can afford it because it is pricey, I would try him on Flutamide first and see how he responds. If he's able to tolerate and does better, I'd stick with the Flutamide. [Posted in FML 6279]