I am sure you know that a lot of older ferrets can look like they are going adrenal, but are just actually losing hair. But, I think the thing with Lupron helping - is not the age of the ferret per se, but the sooner you give the Lupron when you realize there is a problem. At least that seems to be the case with the 4-6 year old ferrets. If you wait 2 years after they show signs of it, instead of sooner, it seems to have less of an effect, but that is just my experience with only a few Lupron ferrets. I have always given Lupron to older ferrets that could not have surgery, but I've never had one that was 9. My oldest was eight that I gave lupron to (SQ). Laryssa [Posted in FML 6168]