Lesley, do you know which vax was used? Many ferrets react to distemper vax. When was his last distemper shot? To get some info about distemper, did you check the links below Sukie's name? I think there was a big discussion about it on the FHL. Dr. Ruth Heller is currently doing a research study on distemper and titers in the blood. You may want to ask your vet to send in BART!'s blood sample to see if he is protected. She will provide info on both distemper and the titer study at the IFC symposium in Pittsburgh Nov. 7-9. -- Renee Downs "Eventually we will realize that if we destroy the ecosystem we destroy ourselves." Jonas Salk "The most effective way to do it, is to do it." Amelia Earhart It's amazing how much can be accomplished if nobody cares who gets the credit! Ferret Emergency Response, Rescue & Evacuation Team (F.E.R.R.E.T.) http://www.ferretemergency.org [log in to unmask] International Ferret Congress http://www.ferretcongress.org American Red Cross http://www.redcross.org [Posted in FML 6018]