Hi Ferrety friends, I've never posted before, but I've really appreciated reading all the comments in my 5 years of ferret ownership. I know there are a lot of postings about adrenal ferrets, so I'm wondering if some of you with experience with non - surgical interventions can help me out during this difficult stage of the illness. Pixie (female) is about 6 years old. She was diagnosed adrenal in May 2 years ago. She began responding to monthly Lupron shots in August of that year. We have been very fortunate that the lupron shots have kept her mostly symptom free for almost 2 years. She still has fur, energy, and a good appetite (thanks to Bob's chicken gravy - Thank You Bob!!) but she has significant vulva swelling. My vet increased the lupron dose and we went in after 3 weeks instead of 4 but the vulva seems to be getting bigger (certainly not decreasing). She says none of the vets on her listserve recommend melatonin but I know someone here posted that they had some vulva decrease with it. Please recommend! The other options she has given me are continued increase of dose/frequency of lupron shots OR lupron implant. They are all expensive and all trial and error. Please share your experience (and your vet's knowledge). If you do melatonin is it with or without lupron? How much? How much money. Worried parents in VT [Posted in FML 5985]