I know you want a large dog, and the ones I am referring to are small, but I think it shows that if puppies grow up around ferrets, they can all learn to live together. We have pugs, and they are great with the ferrets. Our son has a boston terrier and a jack russell. You think terrier you think rat killer. But both these girls grew up around out ferrets, and so, look at them as equals. They would go outside and chase squirrels for hours, come inside, and let the ferrets climb all over them and tease them with toe nibbles. I think starting with a puppy is the important thing. When these pups came home, the ferrets were close to equal in size. Mary in Virginia Owned happily by Bianka the White, Fox, Scarlet and Bear [Posted in FML 5905]