Kimberly: Sometimes the right decision is also the hardest one. We went through something similar early this year, but our Neo had aggressive insulinoma, maybe even pancreatitis, and was deteriorating pretty rapidly, despite surgery and Pred and Diazoxide. When he had his first (and only) violent seizure, despite us diligently giving him food and meds every 4 hours, we knew it was time. We made his last weekend with us peaceful and loving and did everything we could, and he was okay for those last two days. Then on Monday we took him to the vet and held him and spoke to him as he was put to sleep. I still can't speak or write about this without getting tears in my eyes, and this happened back in January. But, we did the right thing FOR HIM. Ferrets live to play, dook, and get into mischief. When that spark is gone, and they cannot muster up enough energy to do anything but sleep and look up at us for help, then they have little or no quality of life left. They are also very stoic, and hide much of the pain they may be experiencing. I believe that the last great act of love that we can show them is to help them to leave this world in peace, with our love and the sound of our voices surrounding them, and not wait until the only thing that they know is pain and desperation. You will know in your heart when this time comes. That is when you must think of your ferret and only your ferret, not your own need to hang on. He needs this from you, he needs you to be strong, and only you can make this decision. Jeff In Memory of Neo Caring for Trinny, Morphy, Baby Girl, and Luna [Posted in FML 5792]