Hi Jason, Here is the destemper vaccine that my vet uses. Canine Destemper adenovirus type 2-parainfluenza vaccine by vanguard my vet told me to give my kids 1cc of pedi-pred 15 mins before i give the vaccine. i do and i haven't had a problem yet. i only know of one case in all the years that he has been using this vaccine that he had a reaction. but there is always the chance, a good one, that the little one that had a reaction, will have another one. they all need to be watched closely for up 24 hours. L [Posted in FML 5756]