My Mikey a bilateral adrenalectomy in September. My vet put him on Prednisone and Fludrocortinsone immediately after surgery. He remained on the medications for 4 months, the amount gradually reduced each month. My vet has done electrolyte (sodium, potassium, chloride and carbon dioxide) panel first 2 weeks after surgery and then monthly. From what I understand, Addison's disease can affect the levels of the electrolytes. Anyway, Mikey is completely off the medications and I am monitoring him for any signs of Addison's. He has been off the medications for a week and is doing great so far. He will go back in for more bloodwork in February. I am not a vet, just sharing my experience :). LISA [Posted in FML 5496]