Hi Marguerite! Try putting them in the tub with a mild solution of hot water, vinegar and washing soda, enough to cover the tube. Let them soak for about an hour, then take a new toilet brush, starting at the opening, insert the brush in the tube and rotate it back and forth moving down the tube, bunching up the part already washed and continue down the tube, make sure there is water still in the tube that has been washed to make sure it doesn't dry with the debris still in the cleaned tube. After completely washing the inside of the tube, drain the tub and turn on the hot water and rinse well, you can hang them up to dry in the tub with the tube inserted into the large opening of a clothes hanger. Hope this helps! =) Chris [Posted in FML issue 5326]