Hi Eric and others I don't think it's wise to continue Nobivac DHPPi vaccine. I'm sure they used to use killed viruses in their vaccine but they have changed that and now do a live vaccine which should not be used on ferrets and they even have a warning on their web page: Nobivac DHPPi contains live, attenuated, freeze dried canine distemper virus, canine adenovirus-2 (CAV2), canine parvovirus and canine parainfluenza virus. This product should not be used in ferrets or mink. http://www.intervet.couk/Products_Public/Nobivac_DHPPi/090_Product_Datasheet.asp Regarding ADV, I think it's more common than you might think, if everybody had autopsies done, we'd know the real extent. Ulrike [log in to unmask] http://www.ferretlove.co.uk [Posted in FML issue 4945]