Krystal, You brought up several good points and I have wondered the same as you. I have contacted 22 vets between yesterday and this morning in an effort to find out if any of them know of side effects or if it might be worth trying the vaccine. Though 17 of them stated to me that ferrets are similiar to dogs and they don't know what reactions may be caused since they have not experienced it, they though it might help bring them extra protection. Two vets said they didn't know and thought a study should be done. The remaining vets said there would be or should not be any reactions. Though this is too small a number for me to attempt the shots with some type of written information on the shots reactions even in dogs or if anyone has tried them on ferrets. I am not sure what you area you live in or if you have several good ferret vets in the area. I have called vets in the tri-state area and they seem not to know if there are any side effects. I would not try to the shots unless all possible side effects are known prior to administering the shot. Also what vaccines were you looking to use? What company or brand? Thanks, Dawn Smith [Posted in FML issue 4944]