http://www.smartgroups.com/message/readmessage.cfm? gid=1423922&messageid=14345&startid=14360 Good questions. 1) Yes, Revolution is effective against ticks, but Frontline spray probably works better for ticks, especially if you have a lot of ticks. 2) Using Frontline spray with Revolution should be safe. Remember Frontline stays on the skin/oil layer and is not absorbed into the bloodstream. 3) Likewise Advantage should be safe with Revolution. 4) Advocate is not available here in the USA. The 2 ingredients are Advantage (Imidacloprid) and Proheart (Moxidectin). Those 2 products are safe for ferrets. Likewise in Australia they have a product called Advantage duo (Imidacloprid and ivermectin), but it is not available over here in the USA. I would check with Bayer about using Advocate on ferrets. If they have a kitten/cat version then they have probably tested it on ferrets too. Over here we have Advantix (Imidacloprid and permethrin), but it is not safe for ferrets or cats! Hope that helps, Jerry Murray, DVM ---- [Sukie Note: BTW, This is turning out to be a bad tick year in some parts of the U.S. There is a LOT of tick info in the FHL Archives in http://fhl.sonic-weasel.org (and I tracked down a number of useful URLs on the topic, too, which are in a few of the posts there).] [Posted in FML issue 4907]