I want to put out a reminder on Melatonin. It is something we touched on briefly not too long ago on the Ferret Health List (a very excellent source for ferret health-related information). While melatonin helps greatly in relieving the symptoms of adrenal disease, it is not a known cure. If you start a ferret on Melatonin before adrenal disease is diagnosed, you run the risk of not spotting it. Hair loss, agression, swollen vulva, ect., while not great symptoms for your ferret to experience, ARE great identifiers of adrenal disease. Adrenal disease usually involves a growth on one or both of the adrenals, which can either be benign or malignant. Malignancies can metastasize to other parts of the body, so catching it early is crucial to a successful surgery. Melatonin, after adrenal disease is diagnosed, is great in relieving the symptoms and helping your ferret grow back their hair, ect. There is some debate on whether or not Melatonin actually prevents adrenal disease, but personally I would rather not take the risk. I know I'm beating a worn-out horse, but I think it's important enough to state again, lest a new ferret owner sees the word "Melatonin" and thinks that it would be a great supplement to use every day. Roary Albuquerque, NM [Posted in FML issue 4867]