There IS *NO VERDICT* (and can be no reliable verdict) for these reasons: 1. Studies on Lupron's abilities are still too new and too small 2. Individuals vary in responses and why is not well enough understood in enough cases 3. While some adrenal growths appear to be shrunken by Lupron not all respond to it and telling them apart well enough without surgery is still not possible So, listen to what your vert says and then decide together. We tend to go for surgery unless the ferret is a poor surgical candidate in which case we go with Lupron and melatonin. For some useful info: http://fhl.sonic-weasel.org and http://www.miamiferret.org/fhc -- Sukie http://www.newyorker.com/fact/content/?050124fa_fact (thinking) http://studentsfororwell.org/ (acting) http://tingilinde.typepad.com/starstuff/2005/01/beagles_arctic_.html (reacting) [Posted in FML issue 4762]