Hello, I have a male ferret, age 3.2 years, good health. He's had some problems with vaccines. The first time I took him in the vet gave him Imrab 3 and Fervac-D in the back of the neck, one right after the other. He developed a lump on his neck, so I took him back and the vet gave him a Flucort injection near the lump. It eventually disappeared. The second year the vaccines were spaced weeks apart and each was given along with a Flucort injection. He had no problems that time. The third time (which was last January) he was again given Imrab 3 and Flucort. Not too long afterwards he started throwing up some blood and was rushed back to the vet for treatment. He recovered from that episode pretty quickly, although he still has a bit of a lump in the back of the neck. After the bad reaction, my vet's advice was to permanently stop both the rabbies and distemper vaccinations, stop taking him outside for walks, and stop exposing him to friends' dogs & ferrets. We did discuss options such as trying a distemper vaccination, possibly with a smaller dose of Fervac-D and pretreating with Benadryl. It was my call, and long story short, I didn't pursue it. With his annual exam coming up, I've found myself rethinking that decision. The potential for me to track canine distemper into the house still weighs on me, and I know he has really missed going for walks and getting together with some of my friends' ferrets. I recently learned of FML, and thought I'd share this story in the hopes that more experienced ferret owners might offer some advice. Given that it has been nearly two years since his last distemper, I'm not sure whether resuming that is even an option. But I'm guessing that some of you would, and could tell me what you'd do if you were stuck in my shoes right now. Thanks. [Posted in FML issue 4713]