http://www.smartgroups.com/message/readmessage.cfm? gid=1423922&messageid=11618&startid=11621 "Blowing the coat", although it sounds dramatic, and can be so, does not produce a bald ferret. It is copious shedding, but not to the point of seeing the skin, and especially not to the degree you describe. You are giving melatonin - I suspect that that is blocking the other adrenal symptoms as well, although they do not have to be present - some ferrets just have one symptom. It is possible for extremely poor nutrition or a severe infection with high fever to produce hair loss, but the most likely cause is adrenal disease. Dr. Ruth ******************************************** Puppies kiss better than most people. [Posted in FML issue 4712]