Joanne, according to vet pathologist Bruce Williams the last time we discussed this sort of thing ferrets have never been shown to have strokes; they just don't form the plaques which dislodge. What they DO get (and cardiomyopathy is one of the big things which can cause these) are thromboses -- thrown clots. We've had that happen causing circling in Meltdown who had it go to the brain. (We have also had another, Chiclet, who pulled one side on her last day -- and completely lost sensory or mobility for her entire lower half -- after a massive fever related seizure with an infection that was not responding to any treatment (one of the first with DIM), but that is not applicable with Bugz.) With thromboses sometimes they will clean up on their own given a bit of time, though if they are thrown to a limb then massage can be used and that seems to help. We had recoveries happen with Meltdown, with cardiomyopathy with her earliest thrown clot but not with the last ones, and another (who was for a while comatose and needing round the clock hospital care, Spot, who later recovered so well that he only had minor mobility damage to one hind foot and never threw another clot from his kidney disease. Some ferrets tolerate mild anticoagulants and can get some protection from these. Soem do not. If a ferret gets serious bleeding from the meds (as Meltdown did) then a small amount of protection can be provided by supplementing extra Vitamin E because that reduces the amount of Vitamin K which is involved in promoting clotting. He is incredibly study sounding for 12 years of age, and you are doing an incredible job for him! [Posted in FML issue 4619]