http://www.smartgroups.com/message/readmessage.cfm? gid=1423922&messageid=10133&startid=10141 No, the vast majority of ferrets can be giving the implants without sedation. I give them a treat such as ferretone, ferret vite, nutical, or laxatone. While they are eating I give them the injection of the implant before they realize what I am doing. In young or hyperactive ferrets, scruff them and hold the treat up to them as you give the implant. I have not taking any of the implants out, and I do not think that is necessary unless there is actually a problem there. So far no problem with the "old" implants under the skin. Hope that helps, Jerry Murray, DVM PS My 2 ferrets will be getting new implants this weekend. [Posted in FML issue 4610]