To the poster that asked if there has ever been a case of canine distemper virus in ferrets - I can tell you from personal experience that yes, ferrets do indeed contract distemper. I run a shelter and back in 1996, I had distemper brought into the shelter by another ferret. Over the course of a few weeks, that ferret and 4 others died from this horrible, preventable disease. In 2001, there was a serious outbreak of distemper in NJ that in one household, they lost 18 of 31 ferrets to canine distemper. Some of these ferrets had no vaccination history; others were very young with no strong history of vaccination. My personal experience has shown that those younger ferrets without a solid history of vaccination are most vulnerable to contracting the virus. Most animal control agencies in your area will be able to tell you if distemper is prevalent in your area. You are much more likely to hear of someone having a reaction to the CDV shot than not having a problem. Most won't post "I had all my ferrets into the vet this year and did not have any reactions!" I know that since 1993, I have vaccinated over 1,000 ferrets (most with the series of 2 shots) and I average about 2 reactions a year to the vaccine. And yes, I use Fervac-D. Lisa Leidig, Head Ferret Shelter Wench in good standing The Ferret Haven "By-the-Sea" www.ferrethaven.org [Posted in FML issue 4618]