Our Vet vaccinates w/ Lupron at first sign of any hair loss that appears Adrenal. The earlier we catch them, the earlier he vaccinates. Sugar, my first Lupron candidate had a naked place at the end of his tail. He got the Lupron and had no problems. My Cocoa, really objected painfully to the injection. He has seemed sore at the hind quarters where he got the shot for several days. No sign of other problem. It's getting better & less sensitive. My Vet freezes Lupron in syringes. This seems to allow them to offer it cheaper by getting larger vials from the supplier. He's very particular about what type of Lupron he gets but I don't the know the particular one he uses. There are some studies going on now to see if Lupron can be used to prevent Adrenal gland disease, which strikes more than half of domestic U.S. ferrets, according to my Vet. Though it will be a few years before we know for sure, for now, it's a chance I find worth taking advantage of. Lupron has been used well in the right situations with both Human men and women, too. I'm hoping it will benefit ferrets as well. Here's to the pioneer Vets who want to solve these problems. In the Blue Ridge with our 2 Lupron babies & their 4 Fuzzy Buddies! [Posted in FML issue 4563]