Marguerite, it is NOT the Galaxy which the vets on the FHL have reported seeing seeing much lower rates of reactions with, it is the new one: the Merial's Purevax CD vax for ferrets which is having their reported much reduced rates of reactions. Of course, reduced rate still means that reactions can happen. It is very important that folks take the careful steps of not giving CD vax and rabies vax in the same appointment, that people remain at the hospital for at least 45 minutes after vaccinations, that they premedicate as their treating vet decides, etc. One other vax reminder, this one for newbies: your new kits need multiple CD vax timed a number of weeks between, and a rabies vax once old enough. The word seems to be getting out better about the kit CD vax this year; many years we FHL moderators hear -- often privately from people too upset to post -- of a number of kits dying absolutely torturous deaths because their new people didn't know about providing the series of shots. I suspect some pet stores or perhaps a major chain's stores have cleaned up their act some in relation to what is said to purchasers so the kits are being protected, either that or there may be fewer "hot zones" this year for CD infection and this is just a temporary reprieve. In relation to titers, the nuances of interpreting such titer levels accurately in ferrets are still lacking. [Posted in FML issue 4546]