That is the only shot my vet will use. He has also found it to have much lower reaction incidents. He has also found that the rabies has caused more reactions in ferrets then the distemper. Hence the reason for giving two separate shots. We always pretreat here with liquid benedry 1 hour before shot time, and knock wood, have never had a single reaction. I have witnessed reactions with both no pretreatment and also benedry shots. Due to showing with the AFA, I have to use Purvac or Fervac with my show ferrets, but the ones who I don't show I have now switched over to the Galaxy shots. I am one who gives both shots on the same day, and have been lucky to have no reactions. I also keep a supply of fluids on hand and am vet assistant trained. Dawn (of LOS) told me about titer studies that were done on ferrets. Galaxy D remains in a ferrets body alot less longer then Fervac or Purvac, which would explain the lower incidents of reactions. I think there should be an official study on titer levels so that we are not over vaccinating our ferrets. Dogs now are on an every 2 year schedule for distemper and every 3 years for rabies. This is due to the titer levels. (which show their immunity to either rabies or distemper). Marguerite TinyPrints Shih Tzu and Rescue http://www.tinyprints-shihtzu.com TinyPrints Ferret Rescue http://www.tinyprintsferrets.com TinyPrints Ferret Rescue Ebay and Half.com Stores http://www.stores.ebay.com/tinyprintsferretrescuestore http://half.ebay.com/shops/shops.jsp?seller_id=1093064 [Posted in FML issue 4545]