http://www.smartgroups.com/message/readmessage.cfm? gid=1423922&messageid=8948&startid=8950 I have to agree with you. If both adrenals are completely removed (that usually means removing part of the wall of the vena cava with the right gland) then the ferret will need replacement hormone supplementation (pediapred and percorten or pediapred and florinef). However some ferrets also have accessory adrenal nodules near the adrenal glands. If these are not removed then they can produce enough of the adrenal hormones. One study found accessory nodules in ~8% of the ferrets they checked (these were healthy, non-adrenal ferrets). Adrenal ferrets probably have a higher rate of accessory nodules. I have found them in the fat pad near the left gland and even on the right side of the vena cava across from the left gland. I have found them most often distal to the right gland and sometimes medial to the vena cava. So you really have to check the fat pads and all around the adrenal glands for the accessory nodules. Plus you have to take part of the wall of the vena cava out to completely remove the right gland most of the time! Hope that helps, Jerry Murray, DVM [Posted in FML issue 4526]