>Before the ferret-specific vaccines I had 2 ferrets (male and female) >who would have very bad reactions... Lisa, thanks so much for your response. Yours is the first I have heard of that records a reaction to the to the "old" vaccine. There may be others. I just don't understand how our West Australian ferrets have no reactions at all. It will probably have to go into the "unknown" basket of why ferrets get adrenal disease, lymphosarcoma and insulinoma. One thing that may be different between our 2 countries, however, is that our vet makes absolutely sure that the vaccine is freshly defrosted minutes before administating it. Ah, the mysteries of ferret health. Love & Dooks, Shirley [Posted in FML issue 4449]