http://www.smartgroups.com/message/readmessage.cfm? gid=1423922&messageid=6796&startid=6798 Hi all, As Sukie pointed out, it is best to do surgery and remove as much of the pancreas as possible to treat insulinoma. If the ferret is a high risk for surgery/anesthesia then treatment with pred, diet, +/- proglycem are the way to go. Chemotherapy with doxorubicin or streptozocin may be the treatment of choice in the near future. Hope that helps clear things up, Jerry Murray, DVM [Posted in FML issue 4349]