Here is the reason why to Not use "Bio-Spot( brand )Stripe-on Flea Control For Cats and Ferrets.", not this year, certainly. We had good results with the uses of Bio-Spot products in years before this one, and had fully expected the same...but with a single tiny spot-on application, just a single drop of the stripe-on, on one of our five-year-old rescues whom we have had in residence for four years and who has never had any sign of reactions before, little Appalonia KissyFace Ferret went into head-thrown-back, gasping convulsions and died within 30 seconds, even as I tried to wash it off of her. When we got to our veterinarian whose offices are exactly 3 minutes away from our Sanctuary, he was very sorry, and advised us not to use any of the Bio-Spot stripe-on on any of the cats or ferrets at all. He stated he'd recently had three cats come in to him killed by the use of the Bio-Spot's Stripe-on and it turned out that the chemicals used to kill fleas in it are over-highly concentrated ( in this year's production) so he firmly recommends that no one use any of the Bio-Spot Stripe-On for either their ferrets Or their cats at all, whatsoever. Poor little Appalonia Kissyface's death saved the lives of 7 cats and 36 other ferrets, including the life of her dear cage-mate, Maggie Mae Moxie Ferret. We sincerely hope this warning may be in time to save many, many more. A much saddened Wes Hurley and Susie Lee of the Ferret and Dove Sanctuary of Pensacola, Fl. http://www.angelfire.com/theforce/ferret_rescuer/index.html [Posted in FML issue 4326]