Anne, take a look at this and read descriptions for when it is not on tip to see if it fits (I can't tell from your description if this fits.): http://www.afip.org/ferrets/chordoma.html The spot on the leg may be a benign mast cell tumor (a common ferret problem). Unlike dogs there has only been one malignant one documented in a ferret and that was an internal one. They can get infected, though, and should be removed with pathology done by a ferret knowledgeable pathologist. The fur thinning needs to be watched in case adrenal neoplasia is starting. Here are sites to help you look up information you need: http://fhl.sonic-weasel.org http://www.ferretcongress.org (click open the crit.refs.) http://listserv.cuny.edu/archives/ferret-search.html ***** It is always important whenever possible to learn about health BEFORE the information is needed because otherwise health problems may not get the timely care they need and for some needless death may occur; preferably use a ferret-knowledgeable vet or one who is willing to learn. When that is lacking check the links to lists of vets at http://www.ferretcongress.org ***** Ticks: http://www.smartgroups.com/vault/ferrethealth/common_parasites.txt http://listserv.cuny.edu/archives/ferret-search.html http://fhl.sonic-weasel.org [Posted in FML issue 4247]