Well - I am of very mixed feelings about this - My Angel had classic symptoms of adrenal. I opted for surgery - it was successful - her left adrenal was very very enlarged and was removed. However, post operatively she threw a clot and died it destroyed half her heart. If I had not opted for surgery, she would be here today. She was hairless but very happy and, up to the point of surgery, was having a very good life. Then I have my Sapp, who also has adrenal disease. He is seven and I opted for Lupron. His first symptom was hind leg dysfunction. With Lupron he is ambulating better and doing all things ferts do - as best he can - not in any pain - still here and happy. SO -- what is best - I do not know - but I really wish that I had NOT opted for surgery for my Angel. Now there is Jo-Jo who has no hair on her tail - - - what to do ? I cannot know right now. I am an RN and know, more than most, the possible post op complications both for humans and fuzzies and I also know that medication available for adrenal is not a cure. Due to my recent experiences - I am opting to do nothing, right now, for Jo-Jo. So I guess I am not treating adrenal disease...... P.S. I did not mention that treating Angel's adrenal disease cost over $600 - it was not important to me - but it may be to others who may not treat adrenal disease due to cost not lack of love. My final thoughts - think very, very carefully about your decision how to treat adrenal disease. And mostly - hug your fuzzies! Z [Posted in FML issue 4183]