Augusta, I am sure that many folks will to respond to you regarding the extreme likelihood of adrenal disease. This is one of the most common ferret disease, your fuzz-butts are ~middle-aged, and your boy has one the most commonly reported symptoms (after above-the-tail hair loss). But, his symptoms don't mean that HE has the disease! With adrenal disease, sex hormones can get way out-of-wack which can cause male aggression or return-to-male-intact-sexual-behavior, even if the FEMALE has the screwy hormone levels! There is much information available about this disease (start at http://www.afip.org/ferrets/index.html), and there are many possible symptoms, although the disease can be asymptomatic until fatal complications arise, so don't put this off. Please have _BOTH_ ferrets checked at the most ferret-knowledgeable vet you can find, and get a second opinion if the first vet doesn't plan to surgically treat or medicate whichever ferret is suspected to have the disease. My fixed male ferret, Sherlock, (age unknown-guessed at ~7?) exhibited _just_a_few_ return-to-male-behavior episodes in February. Both my ferrets got checked by our vet, and since then we were watching for additional symptoms to figure out who had adrenal disease. No other adrenal diseases symptoms developed in either ferret for months, and Sherlock completely stopped the return-to-male-behavior! Just recently my female, Samantha's (age also guessed at ~7) vulva became somewhat enlarged, so we went back to the vet and the vet & I now think Samantha has the disease (although I am still looking for more syptoms from him, as both could have it!). Samantha will undergo surgery to locate and remove the diseased gland(s), then I will keep her on a supplement to help balance adrenal gland function. I use Azmira's "Stress & A'Drenal Plex." You may not want to start the supplement until you are _sure_ which ferret has the disease, just in case it helps enough to delay the onset of symptoms essential for diagnosis! I had been giving it to both of mine after the onset of symptoms in February, but I eventually stopped when months later no other symptoms were evident. 10 days after taking them off the supplement Samantha's vulva enlarged! I am not sure that this time correlation is based on causation. I had been giving it to my last ferret with confirmed adrenal, and it didn't diminish his symptoms, although his disease had asymptomatically progressed farther them any of us knew at the time. Of the last 5 older-ferret rescues I have adopted, 2 are still with me and 1 has adrenal disease, and 3 have passed and 2 of them had adrenal disease. Get your little ones to the vet, and give your ferrets a little snuggle from me! Best of luck. I am not a vet. Jenny [Posted in FML issue 4182]