Hello, I have used rescue remedy in traveling with a 5 healthy ferrets about a year ago. I think it helped them. Last weekend I had to take a 8 hour trip from Atlanta to Camp Lejuene, my brother left for Kuwait. I took 4 ferrets that I thought I would worry about the whole trip. I decided that since they had issues not to use it. I had a 7 year old she has that recurring right adrenal issue and cancer. I first thought of giving that too her. But, I decided not to given any of them anything. Just more talking and holding on the trip. Since, I was by myself I would not play the radio and talk to them. But, since you ferret has these medical issues. Consult your vet. But, I would take the bottle in to the vet to let them see the ingredients. Have a safe trip. Benita [Posted in FML issue 4078]