>Now if someone could put my mind at ease as to how a 1.5 - 3 lb ferret >can handle 1 mg of melatonin when the adult human dose is 3 mg, it would >make me feel a lot better about such a "whopping dose" Although I'm not a vet maybe I can shed some light on this. As it was explained to me, the "normal" human dose of 3 mg of Melatonin is meant to help regulate sleep patterns, such as recovering from jet lag. Larger doses inhibit the production (I believe) of certain hormones in the body, which is what you want to do with a ferret whose adrenal glands are producing excessive sex hormones. The 1 mg/kg dose of Melatonin accomplishes this fairly effectively from what I've seen in our ferret who have been on it. Dick B. 4 Li'l Paws Ferret Shelter For a downloadable copy of my "Ferret Owner's Manual," visit http://4lilpaws.org [Posted in FML issue 3980]