http://www.smartgroups.com/message/readmessage.cfm?gid=1423922&messageid=1930 To answer the other parts of your question, will melatonin work. Since it is likely an adenocarcinoma (based on return of sexual behavior), I do not know if melatonin by itself will work. Melatonin can be used with Lupron or it can be used after the surgery to help the haircoat come in quicker. Lupron should be drawn up into syringes and frozen for storage. No one knows for sure how long it can be stored frozen. Defrost and give the injections into a muscle (rear leg). Hope that helps, Jerry Murray, DVM [Posted in FML issue 3944]