http://www.smartgroups.com/message/readmessage.cfm?gid=1423922&messageid=219 >Molly had adrenal/insulinoma surgery two weeks ago and my vet discovered >a big liver cyst and additional smaller ones. There was a dark red >discoloration throughout and she was concerned that it might be >adenocarcinoma. I finally got Molly's pathology results yesterday and >she doesn't have cancer. Yay! She has benign liver cysts. While I would not want to be the bearer of bad tidings, many low grade biliary cystadenocarcinomas will have the appearance of benign cysts, but will continue to grow and replace functional liver over time. Judging from your description, I am worried about this possibility. One way to track this without opening her up again would be to do an ultrasound now and in a couple of months and compare the two to see if there has been an increase in size. Prednisone or adrenal disease do not cause the appearance of these lesions. If this is indeed a low-grade malignancy, one would expect growth over time, and eventually, if not complete excised, can result in destruction of significant amounts of liver and ultimately liver failure. with kindest regards, Bruce Williams, DVM [Posted in FML issue 3840]