This is an uncommon non-specific change (the dandruff) and it is not directly attributable to adrenal disease or even skin disease. The way that dead skin exfoliates is well-programmed in all animals, and it generally come off one cell at a time. When something upsets this balance, and it comes off as sheets of cells, it gives the appearance that we know as dandruff, or dry seborrhea. Unfortunately, many things can do this; any health problem has the ability to do it. At this point, regular bathing and grooming is the best thing that you can do, and watch carefully. The hair loss, even in spite of new growth is concerning, but I don't personally have any red warning lights flashing yet on this one. with kindest regards, Bruce Williams, DVM [Posted in FML issue 3776]