Hi all - I never post anything, but this question really got to me. I have been owned by 3 ferrets in my life. My first little girl died after adrenal surgery at 4 1/2 years old. My boy, Taz was recently diagnosed with insulinoma and we are having a really hard time controlling his glucose levels. He is almost 7 years old. My third ferret is a 4 year old little girl who was a rescue - - as of right now (knock on wood) she is not sick. It tears my heart out to watch my little boy be sick. It literally makes me crazy that I am just waiting for the girl to start showing signs of adrenal, or something else. The fuzzies steal your heart so completely. They are little angels with fur. I just don't know if I will be able to get anymore...knowing ahead of time that one day they are going to get sick...then they will suffer, and then they will die. I hate to be so negative, because I love ferrets so much. Ever since I got my first one in 1994 I have been hooked. I just don't know if I can continue to go through it. On this note, I must ask for help. Has anyone has had an insulinoma ferret that went from low blood glucose levels to extremely high levels without surgery? My Taz (age 6 years 11 months) was presenting with low glucose levels, we put him on Pred...and then weeks later when we checked his levels again they had sky-rocketed and have remained extremely high. He has since been taken off the Pred completely (obviously) and we have started him on insulin. So far he has been mostly resistant to the insulin and his blood glucose levels remain incredibly high. I am very worried about him. He is starting to show hind end weakness, he drinks & urinates very frequently and his enery is low. I am working with a wonderful veterinarian, but of course I am looking for help & answers from anywhere & everywhere. Anything to get my Taz stabilized at the very least. As you can imagine, I am feeling desperate. Any and all help, advice, anecdotes etc is appreciated! Thanks so much. Shelby, Taz & Silky Bear [Posted in FML issue 3774]