Thanks to all who have replied to my post yesterday. I have some updates from my vet (of whom I asked many questions today.) He called my work to find out how P.B. was doing and plans on calling again tomorrow. He tells me that typically insulinomas are pin-sized and so the x-ray taken of P.B. wouldn't necessarily discount that possiblity. The reason the low blood sugar is a bit of mystery is this: Each time P.B.'s blood sugar is found to be low, his insulin levels are at a normal level. In any case, the shot that he was given yesterday was Depo Medryl (sp?) which is a progesterone type steroid released over weeks. He prefers it to daily prednisone because it can maintain glucose levels better. He wants us to keep a very close eye on the booger to make sure he doesn't have a seizure (little guy has had a couple, probably brought on by the low blood sugar I guess) with instructions to call him at work or at home if necessary. To complicate matters, a highish level of clostridium was found in his stool. We have him on anti-biotics for that. Thanks to all of you. I appreciate the support, advice, and kind words. Matthew in CO with P.B. (missing Sherlock and Gryphon) [Posted in FML issue 3749]