Hi X, If it has been a year since her left adrenal gland was removed, and she is still having adrenal signs then it is likely that her right adrenal gland is the problem. Since she is just 3 years old then surgery is the first choice. Lupron and/or melatonin can be used to treat adrenal gland disease. Melatonin is "the natural product" that can be used in either the tablet form or liquid form (1mg once a day about 8-9 hours after sunrise), or in the injectable (mink) implant form (every 4 months). The vets down at Texas A&M and I have just started a project with the injectable implants. So far the only side effect is lethargy for the first few days. It is to early to comment about results; however, today I rechecked one that is 3.5 weeks post melatonin implant. Lots of new "peach fuzz." Hope that answers your question, Jerry Murray, DVM PS If your girl has had a swollen vulva for the past year then it is time to do a CBC to check for anemia. [Posted in FML issue 3743]