I have never vaccinated my ferrets for distemper, only rabies, but i want to take them to a ferret event, so they have an appointment to get their distemper shots on Wednesday. My question is, what do I look for for signs of a reaction, and how long can it take for them to have a reaction? I am going to administer Benadryl before they go, and I am planning on spending an hour waiting at the vet after the vaccine. Amber reacted slightly to her rabies shot the last time with a little dry heaving about 10 hours after the shot, but she was fine after that. I just want to know what to look for and for how long. I'm figuring 24 hours, but I wasn't sure if it should be even longer than that or not. Any input would be greatly appreciated. Kelly White Southampton, Massachusetts with Amber and Jenna, the weasels and T.J., Natasha, Belle, Smokey, and Parker, the kitties and Tim, the husband [Posted in FML issue 3689]