There is only one rabies vaccine approved for ferrets - IMRAB-3. The "other" distemper vaccine is a new one: Purevax from Merial. If your vet hasn't heard of it, insist that he or she check it out. (My vet thought Purevax was only for cats.) There is a picture of the box, that clearly says "ferret" in the latest Ferrets magazine. Your vet can also use Galaxy-D from Solvay. This has not been proven effective in ferrets and so isn't approved by the USDA. Therefore the American Ferret Association does not recommend it. It does appear to be safe for them, and may very well be effective, it just hasn't been proven to be. Both Purevax and Galaxy-D cause far fewer bad reactions than Fervac-D. They are both much "cleaner" vaccines. Roger, Digger, Bear, Pepper and Badger [Posted in FML issue 3680]