This summer my vet (a very experienced ferret vet) shocked me when she mentioned that my oldest ferret (only 2 1/2 years at the time) had possible adrenal signs beginning. She pointed out areas of slight hair loss (on the lower belly and bottom of feet) and then casually said that we would keep an eye on her (as tears were welling up in mine). Since then I find myself doing daily or weekly adrenal assessments. I have since looked into many sites with adrenal information so that I'll be prepared to notice symptoms and know what happens next. I find it a very confusing and blurry line to susupect adrenal. I would like to explain the changes I've noticed in her and am hoping that owner's whose fuzzies have battled adrenal can tell me personal signs or experiences they had with their babies. Mikette (my possible adrenal baby) lost more fur on her lower belly, and bottom of feet during the summer - those spots became pretty much bare. The vet said it was fine to wait til her next appt in Oct. By then she had grown all that fur back. I was afraid it was just new winter growth and that she would lose that as well. She's been fine since then until just this past week when I've noticed her fur down the insides of her back legs seems a bit thinner. Her vulva has not been swollen at all, although I did notice what seemed like remains of discharge during the summer (when I was on high alert for adrenal). She got very thin during the summer and fall (you could feel her chest bones sharply). I gave her Ferretvite every other day and the last few weeks her weight has finally come back. She sleeps a bit more in the morning, but then is just as active when she wakes up. During the summer I noticed her cleaning her two fuzzie sister's ears a lot, which is unlike her - but she seems to have stopped this nurturing. She is sligtly less aggressive with humans and her fuzzie sisters during play, but she still wrestles, chases, and plays. For awhile she seemed to have less of an interest in treats, it was as if she couldn't smell them. If one was broken then she would want it more. She was still eating her kibble. I noticed a strong ferret scent seemed to come from her. They all get stinky ears right before grooming days, but her scent just seemed to come from all over her body. It was the type of scent I always noticed on some friend's ferrets but had never smelled on mine (maybe her scent was just changing so I became more aware of it). Her fuzzie sisters still cuddle and sleep with her. My last concern is that she often makes wimpering noises in her sleep (I don't recall her doing this at all before). It is usually in the evening if she's taking a solo nap in the cage. If I try to sweet talk her and pet her it may stop for a moment, but then continues. If I take her out of the cage and let her sleep on my belly then it stops. I'm sorry this post got so long, but if anyone has any similiar experience, advice, or adrenal information please let me know. Mikette is still seeing her vet and will have another check-up this spring or earlier, but the wait and watch routine is difficult! Thanks Risa [Posted in FML issue 3662]