Hello, From past experience: Yes, air purifiers work with ferret odor. However, you need to know how big of an area you want to cover. Get out a tape measure and measure the room/rooms you want, because depending on the size of the area, that will be which air purifier you have to get. Also be forewarned: cheap ones do not work. You'll have to plunk down anywhere from $80 to $150 on the purifier itself. The inner filter needs changed every 3 months if you are covering a large area, and if you are filtering out other smells like a cigarette smoke. If you aren't, then you may be able to last longer. The inner filters are also expensive. No one ever puts them on sale. They're anywhere from $40 to $60 dollars. The outter charcoal filters are a little cheaper, and you can buy big strips of it from a home improvement place and cut them down to size much cheaper than buying them precut. The filter really did work for its purpose, and I recommend one. It's going to be expensive to set up, but to me, it was worth it. Julie - Missing fuzzbutts in Ohio [Posted in FML issue 3498]