Hi X, You are asking a tough question. Do the benefits of surgery (remove the adrenal gland that has "regrown") to treat the adrenal gland disease outweight the risk of surgery on a heart patient (death from anesthesia)? If he makes it through the surgery then yes, but if he dies then no. The heart problem would scare me away from surgery. If it were my ferret then I would go with Lupron. Hope that helps, Jerry Murray, DVM PS- there seems to be some confusion and incorrect use of the term "ectopic" in regards to adrenal glands. Ectopic means having adrenal tissue outside the adrenal gland (usually in the fat pad by the adrenal gland). Most of you are describing adrenal glands that were not completely removed (part of the capsule or gland remains) and with time the gland "regrows" and becomes a problem again. [Posted in FML issue 3516]